2006 서울대학교 수의과대학 학사 졸업 

2008 서울대학교 수의과대학 석사 졸업 (실험동물의학 전공)

경력
2010.12~2020.07 서울대학교 의학연구원 연구부교수 

2011~현재  서울여자대학교 동물실험윤리위원회 위원
2020.08~  서울대병원 융합의학과 임상교수 

마크로파지 (종양마크로파지, 장마크로파지)

종양면역학

점막면역학

동물모델링 (마우스, 제브라피쉬)

- 식품의약품안전처 대체시험법 개발 검증 기반 구축 연구 (2020년~2021년, 20183대체기524, 면역세포 등을 이용한 면역독성 평가기술 개발 연구)

- 한국연구재단 기본연구 (2017년~2021년, 과제번호 2017R1D1A1B04031161, 

마크로파지 특이적PKA 저해제를 통한 유방암 면역치료법 개발과 검증)

1) Nat Rev Gastroenterol Hepatol. 2019 Sep;16(9):531-543. Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD. NaYR(제1, IF 23.57), Stakenborg M, Seok SH, Matteoli G. 

1) Cell Rep. 2020 May 12;31(6):107643. doi: 10.1016/j.celrep.2020.107643. Protein Kinase A Catalytic Subunit Is a Molecular Switch That Promotes the Pro-tumoral Function of Macrophages. NaYR(제1, IF 7.815), Kwon JW, Kim DY, Chung H, Song J, Jung D, Quan H, Kim D, Kim JS, Ju YW, Han W, Ryu HS, Lee YS, Hong J, Seok SH

2) Mol Cell Biol. 2020 Jan 3. pii: mjz113. doi: 10.1093/jmcb/mjz113. Pyruvate dehydrogenase kinase is a negative regulator of interleukin-10 production in macrophages. NaYR?(제1, IF 4.671),, Jung D, Song J, Park JW, Seok SH.

3) Cancer Lett. 2018 Jan 28;413:46-58. Metabolic features of macrophages in inflammatory diseases and cancer. NaYR?(제1, IF 6.491), Je S, Seok SH.

1) J Immunol. 2016 Nov 15;197(10):4101-4109. GM-CSF Induces Inflammatory Macrophages by Regulating Glycolysis and Lipid Metabolism. NaYR(제1, IF 4.718), Gu GJ, Jung D, Kim YW, Na J, Woo JS, Cho JY, Youn H, Seok SH.

2) Mol Cells. 2016 Oct;39(10):734-741. GM-CSF Grown Bone Marrow Derived Cells Are Composed of Phenotypically Different Dendritic Cells and Macrophages. NaYR(제1, IF 3.533), Jung D, Gu GJ, Seok SH.

3) Sci Signal. 2015 Nov 24;8(404):ra121. The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production. NaYR(제1, IF 6.481), Jung D, Gu GJ, Jang AR, Suh YH, Seok SH.

4) Mol Cell Proteomics. 2015 Oct;14(10):2722-32. doi: 10.1074/mcp.M115.048744. Epub 2015 Jul 30. Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF) Grown Macrophages Derived from Murine Bone Marrow Cells. NaYR(제1, IF 4.828), Hong JH, Lee MY, Jung JH, Jung D, Kim YW, Son D, Choi M, Kim KP, Seok SH.

5) Eur J Immunol. 2015 Sep;45(9):2661-71. Endogenous prostaglandin E2 potentiates anti-inflammatory phenotype of macrophage through the CREB-C/EBP-β cascade. NaYR(제1, IF 5.179), Jung D, Yoon BR, Lee WW, Seok SH.

6) PLoS One. 2015 Feb 13;10(2):e0118203. Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype. NaYR(제1, IF 2.776), Yoon YN, Son D, Jung D, Gu GJ, Seok SH.

4) Clin Cancer Res. 2020 Jan 1;26(1):265-273. Identification of FES as a Novel Radiosensitizing Target in Human Cancers. Kim BH, Kim YJ, Kim MH, NaYR?(공동, IF 8.911) , Jung D, Seok SH, Kim J, Kim HJ.

5) Front Immunol. 2018 Sep 18;9:1984. Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Chang S, Kim YH, Kim YJ, Kim YW, Moon S, Lee YY, Jung JS, Kim Y, Jung HE, Kim TJ, Cheong TC, Moon HJ, Cho JA, Kim HR, Han D, NaY(공동, IF 6.429), Seok SH, Cho NH, Lee HC, Nam EH, Cho H, Choi M, Minato N, Seong SY.

2) Invest Ophthalmol Vis Sci. 2018 Jul 2;59(8):3747-3754. Lactic Acid Upregulates VEGF Expression in Macrophages and Facilitates Choroidal Neovascularization. Song J, Lee K, Park SW, Chung H, Jung D, NaYR(공동, IF 3.812), Quan H, Cho CS, Che JH, Kim JH, Park JH, Seok SH.

7) Biol Open. 2016 Aug 15;5(8):1118-27. An in vitro model of granuloma-like cell aggregates substantiates early host immune responses against Mycobacterium massiliense infection. Je S, Quan H, NaY(공동, IF 1.962), Cho SN, Kim BJ, Seok SH.

8) PLoS One. 2016 May 18;11(5):e0155685. Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth. Je S, Quan H, Yoon Y, NaY(공동, IF 2.776), Kim BJ, Seok SH.

9) Mol Cancer. 2015 Feb 3;14:23. Male-specific hepatitis B virus large surface protein variant W4P potentiates tumorigenicity and induces gender disparity. Lee SA, Kim H, Won YS, Seok SH, NaY(공동, IF 10.679), Shin HB, Inn KS, Kim BJ.